Latest Research Reveals a Connection Between Marijuana Use and Cardiovascular Disease 

As marijuana legalization expands across the U.S., researchers continue to investigate its potential health risks, particularly its impact on cardiovascular health. While many people perceive cannabis as a “safer” alternative to tobacco, several recent studies suggest that smoking or ingesting THC may contribute to vascular dysfunction and increased heart disease risk.

The Link Between Marijuana and Heart Health

It’s well-known that chronic tobacco smokers and those exposed to secondhand smoke experience poor endothelial function, a form of coronary artery disease that slows blood flow to the heart. When your endothelial cells fail to work properly, you may face a higher risk of heart attack, stroke and other cardiovascular complications.

Marijuana smoke contains many of the same toxic chemicals found in tobacco smoke. Knowing this, researchers from the University of California, San Francisco, examined how THC affects heart health and published their findings in a peer-reviewed study in JAMA Cardiology in May 2025. 

The team categorized participants into three groups – marijuana smokers, THC-edible users and nonusers. The study revealed that vascular capacity declined significantly among cannabis users, with smokers experiencing a 42% reduction and edible consumers seeing a 56% decrease compared to nonusers.

Breaking Down the Findings

The UCSF study highlights several potential dangers, particularly for young, otherwise healthy adults who may assume marijuana carries minimal risk. Here are some leading takeaways about how cannabis use can affect your heart health and circulation.

• A retrospective analysis of over 4.6 million people under age 50, published in JACC Advances, found that marijuana users faced a sixfold increased risk of heart attack, a fourfold risk of ischemic stroke and a threefold risk of cardiovascular death compared to nonusers.
• Daily marijuana use can increase your coronary artery disease risk by one-third, even if you’ve never smoked tobacco.
• Edibles, previously considered a benign alternative, can also cause significant vascular impairment, suggesting that THC consumption – not just smoke inhalation – may contribute to cardiovascular risks.

What This Means for Marijuana Users

Despite its growing acceptance, marijuana does not appear to offer any benefits for preventing or treating cardiovascular disease. The American Heart Association has issued multiple scientifically backed warnings that cannabis use may increase the likelihood of life-threatening cardiovascular events like strokes and heart attacks.

• Studies cited in the AHA’s 2022 statement found that marijuana users experienced 17% to 24% more strokes than non-users.
• Cannabis can temporarily increase your blood pressure, which may contribute to long-term hypertension and heart disease.
• Additional research links marijuana use to higher rates of heart attacks, heart failure and atrial fibrillation.

While marijuana keeps gaining legalization and acceptance for recreational and medicinal purposes, these studies highlight the importance of understanding its potential health consequences. As research continues, experts recommend that people – especially those with existing heart conditions – consult with their health providers about the risks associated with cannabis use.

Expert Recovery Coaching for Marijuana Addiction

Addiction is another significant danger of frequent marijuana use. Overcoming a cannabis use disorder requires compassionate, professional guidance. At R&A Therapeutic Partners, Ray Estefania and Ana Moreno bring over 40 years of combined experience in mental health and addiction counseling, supporting you in your goals of achieving long-term sobriety.

Our approach includes:

• Ongoing coaching to manage life’s challenges and prevent a relapse.
• Tailored strategies for reinforcing healthy habits and maintaining your sobriety in everyday life.
• Dedicated assistance to help you stay on track as you rebuild your confidence.

Reach out today to learn more about our suite of specialized services.

At R&A Therapeutic Partners Raymond Estefania and Ana Moreno specialize in substance use and mental health disorder evaluations, treatment, intervention and therapeutic/educational consulting for clients throughout the greater South Florida area, as well as nationally and internationally. For more resources and information please visit Therapeutic-Partners.com or on Facebook.